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Often, antibiotics are released into the environment only slightly transformed, or even unchanged and conjugated to polar molecules. Chemical and physical behaviour in the soil depends on the molecular structure of the pharmaceutical. An overview of the fate of antibiotic compounds in soils and the sorption coefficients in soils, sediment and slurry was also published by Thiele-Bruhn (2003).With regard to their various structural classes, antibiotics are ionised, amphiphilic or amphoteric and for this reason, adsorption to soils take place.
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